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Metabolic Syndrome and Related Complications

by Admin

Metabolic Syndrome refers to disorder and conditions related to metabolism. Metabolic syndrome is coexistence of abdominal obesity, hyperglycemia, hyperlipidemia and hypertension that causes cardiovascular diseases, diabetes and their complications, low quality and short lifespan.


It is possible to prevent or delay metabolic syndrome, mainly with lifestyle changes. A healthy lifestyle is a lifelong commitment. Successfully controlling metabolic syndrome requires long-term effort and teamwork with your health care providers.

People who have metabolic syndrome often have two other conditions: excessive blood clotting and constant, low-grade inflammation throughout the body. Researchers don't know whether these conditions cause metabolic syndrome or worsen it.

What is Metabolic Syndrome ?

Metabolic syndrome is a cluster of metabolic disorders. It represents a clustering of risk factors related to an elevated risk of cardiovascular disease and type 2 diabetes.

5 variables of Metabolic Syndrome

According to The National Institutes of Health guidelines Metabolic syndrome occurs when a person has the following three or more measures:

    Large waist »

  • Abdominal obesity (waist circumference greater than 40 inches in men and 35 inches above women)
  • High triglyceride level »

  • Triglyceride level per milliliter of blood (mg / dL) or more than 150 mg level
  • Reduced "good" or HDL cholesterol »

  • HDL cholesterol less than 40 mg / dL in men or less than 50 mg / dL in women
  • Increased blood pressure »

  • Mercury (mm Hg) or greater than 130 mmol systolic blood pressure (peak number) or diastolic blood pressure of 85 mm Hg or higher (lower number)
  • Elevated fasting blood sugar »

  • 1 mg / dL or more fasting glucose

Risk for metabolic syndrome increases with age.

Risk factors
The following factors increase your chances of having metabolic syndrome:

  • Age. Your risk of metabolic syndrome increases with age.
  • Ethnicity. In the United States, Hispanics— especially Hispanic women — appear to be at the greatest risk of developing metabolic syndrome.
  • Obesity. Carrying too much weight, especially in your abdomen, increases your risk of metabolic syndrome.
  • Diabetes. You're more likely to have metabolic syndrome if you had diabetes during pregnancy (gestational diabetes) or if you have a family history of type 2 diabetes.
  • Other diseases. Your risk of metabolic syndrome is higher if you've ever had nonalcoholic fatty liver disease, polycystic ovary syndrome or sleep apnea.
  • Complications
    Having metabolic syndrome can increase your risk of developing:
  • Type 2 diabetes. If you don't make lifestyle changes to control your excess weight, you may develop insulin resistance, which can cause your blood sugar levels to rise. Eventually, insulin resistance can lead to type 2 diabetes.
  • Heart and blood vessel disease. High cholesterol and high blood pressure can contribute to the buildup of plaques in your arteries. These plaques can narrow and harden your arteries, which can lead to a heart attack or stroke.
  • Prevention of metabolic syndrome?

    Preventing metabolic syndrome requires long-term effort and teamwork with your health care solutions.

    Eat a healthy diet. In general, a diet that's low in saturated fats, trans fat, cholesterol, and salt -- and high in fruits, vegetables, lean protein, beans, low fat dairy, and whole grains -- has been shown to help people with high blood pressure and a higher risk of cardiovascular disease.

    1. 2008, over 68 xanthone-type compounds had reportedly been derived
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